Semler Scientific, a medical technology firm, has made a substantial move in the cryptocurrency space by purchasing 185 BTC for $20 million between May 23 and June 3. This investment raises the company’s total Bitcoin holdings to 4,449 BTC at an average acquisition price of $107,974 per coin. According to a filing with the US Securities and Exchange Commission (SEC) on June 4, Semler's total investment now totals $410 million, bringing its current Bitcoin market value to about $472.9 million, reflecting a return of 26.7% since it began accumulating Bitcoin back in May 2024. Despite continuous purchases over the past year, including a $50 million boost to its reserve in May, the strategy hasn't captured much investor interest, with the company's stock down 37% in 2025. However, there has been a slight share price increase of 16% since the announcement of its Bitcoin reserve. The mixed results continue as companies holding Bitcoin reserves face varying outcomes in share performance, with some others seeing gains while Semler's remains lackluster. Bitcoin itself has seen significant volatility in 2025, having reached a high of $112,000 before pulling back to below $77,000 amid economic uncertainties. Notably, there are currently about 3.4 million BTC held in various treasuries—mainly by public companies and exchange-traded funds, while governments hold a smaller portion.